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Inogen’s Oxygen Concentrators Clinical Efficacy

doctorInogen and its portable oxygen concentrator, the Inogen One, are grounded in peer-reviewed and published clinical research. Since its inception, Inogen has been dedicated to the design, development, and manufacture of clinically efficacious oxygen technologies. As an innovator of oxygen technology and portable oxygen equipment, Inogen’s purpose is to improve lives through respiratory care.

Inogen, Inc. is a leading global medical technology company offering innovative respiratory products for use in the homecare setting. Inogen supports patient respiratory care by developing, manufacturing, and marketing innovative best-in-class portable oxygen concentrators used to deliver supplemental long-term oxygen therapy to patients suffering from chronic respiratory conditions. Inogen partners with home medical equipment providers and distributors to make its oxygen therapy products widely available allowing patients the chance to remain mobile.

Specific Research on Inogen Portable Oxygen Concentrators

We have completed and published several reports focused on clinical data supporting the Inogen One oxygen system. 

Peer-reviewed and published research has suggested that an oxygen setting selection on the Inogen One based on daytime active daily living/ambulation appears to produce effective nocturnal oxygen therapy as evidenced by a mean sleeping SpO2 of 92% and no clinically significant desaturation during the study.[1]

Inogen has also conducted research to examine nocturnal oxygenation with continuous flow and the Inogen One portable oxygen equipment among a group of established Long Term Oxygen Therapy users with chronic lung disease.

The researchers concluded that SpO2 and HR remained clinically equivalent compared to the values while on continuous oxygen at baseline. The study suggests that daytime pulse dose titrations may be effective in determining nocturnal oxygen requirements. Titrating the Inogen One setting to the daytime SpO2 on continuous oxygen provided adequate oxygenation, even during sleep.[2]

Peer-reviewed and published clinical studies conclude that the Inogen One can provide supplemental oxygen for most ambulatory patients during all phases of daily activities and during sleep. [1,2]


  1. Stegmaier JP. Chatburn RL, Lewarski JS. Determination of an Appropriate Nocturnal Setting for a Portable Oxygen Concentrator with Pulsed-Dosed Delivery. Abstract. Respir Care November 2006;51(11): 1305.
  2. Chatburn RL, Lewarski JS, McCoy RW. Nocturnal oxygenation using a pulsed-dose oxygen-conserving device compared to continuous flow. Respir Care. 2006 Mar;51(3):252-6. PMID: 16533414.
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