Key Takeaways
- 5L concentrators deliver up to 5 LPM, making them well-suited for patients with mild to moderate hypoxemia that can be corrected with ≤5 liters per minute (LPM) of oxygen delivered via nasal cannula. 10L models deliver up to 10 LPM for high-flow oxygen therapy (typically 6–10 liters per minute) when patients have moderate to severe hypoxemia that cannot be corrected with standard low-flow oxygen (1–5 LPM). Oxygen flow should be titrated to the lowest effective dose that maintains safe saturation.[1,2]
- 5L units typically weigh less than 20 pounds making them preferable for patients desiring mobility. 10L models weigh between 42-60 pounds and are designed primarily for stationary home use due to their weight and higher oxygen outputs.
- 5L concentrators range from $600-$2,400 and consume 275-400 watts. 10L units typically cost $2,000-$4,000 or more and require 400-1,000+ watts.
- Some patients benefit from a stationary unit at home for overnight use and a portable concentrator for daytime activities.[1,3]
- Patients using oxygen concentrators should have a backup oxygen source available at all times to ensure uninterrupted therapy.[3]
What Are 5-Liter and 10-Liter Oxygen Concentrators?
Oxygen Concentrator Definition and Function
Oxygen concentrators work by pulling in the air around you, filtering out nitrogen through columns called sieve beds to deliver 90-95% purified oxygen. The concentrated oxygen is then delivered through a nasal cannula or mask, as prescribed by your healthcare provider. Unlike compressed or liquid oxygen tanks that require refills, concentrators continuously purify surrounding air — no deliveries and no tanks to swap out.[3,4] Every patient is unique and may have different oxygen requirements, so it’s important to talk to your health care provider about your prescription.[1]
5-Liter Oxygen Concentrator Overview
A 5-liter home oxygen concentrator provides up to 5 liters per minute (LPM) of continuous oxygen flow and is commonly used for patients with respiratory conditions that produce mild to moderate hypoxemia such as COPD or interstitial lung disease. These units are designed for everyday home use but offer greater mobility than higher-capacity systems, with many models weighing 33–36 pounds and some advanced designs weighing under 20 pounds. They typically deliver 90–95% oxygen purity, operate quietly, and consume less power than larger devices, making them a practical option for patients who need reliable oxygen support without high-flow requirements.[1-4]
10-Liter Oxygen Concentrator Overview
A 10-liter home oxygen concentrator delivers up to 10 LPM of continuous oxygen flow and is intended for patients with more advanced oxygen needs, including severe COPD, advanced pulmonary fibrosis, or significant chronic hypoxemia that cannot be corrected with lower-flow devices. These units are stationary systems designed exclusively for home use due to their size and power requirements, typically weighing 42–60 pounds. They provide higher oxygen output to maintain safe saturation levels in patients who require ≥5 LPM and are often used as part of long-term oxygen therapy (LTOT) for progressive lung disease.[1-4]
Choosing Between 5-Liter and 10-Liter Models
Assessing Your Oxygen Flow Requirements
Your physician prescribes oxygen therapy measured in liters per minute based on your specific respiratory condition. This prescription defines whether you need continuous flow or pulse dose delivery and determines your equipment capacity requirements.[5]
It is important that you do not adjust your oxygen flow rate without consulting your doctor first, as proper dosing maintains your health status and prevents complications.[6]
Evaluating Your Daily Activity Levels
Oxygen consumption varies based on your physical state and activity patterns.[1,2] Those who remain active or travel regularly may find that portable options help them maintain their independence. Portable oxygen concentrators (POCs) are typically smaller and lighter than 5L or 10L stationary units, and offer more flexible power sources, but they tend to have lower oxygen output than stationary units and may not be adequate for patients with higher oxygen needs.[3]
On the other hand, patients who require oxygen primarily during sleep or while at rest often do well with a stationary concentrator set up at home, such as a 5L or 10L unit.[1,2] Work with your healthcare provider to match your supplemental oxygen prescriptions to the best device for your lifestyle.
Home Use vs. Portable Oxygen Needs
Your healthcare provider will determine the appropriate oxygen delivery device based on your medical needs and lifestyle. Whether you choose a stationary oxygen concentrator or a portable oxygen concentrator, both types of Inogen systems are designed to be moved around your home as needed. Portable oxygen concentrators offer added flexibility, allowing you to continue your prescribed oxygen therapy outside the home, during travel, or while maintaining an active lifestyle. Stationary units provide continuous-flow oxygen for patients who require a steady, uninterrupted oxygen source.[1-3]
It is important to maintain a secondary source of oxygen for safety and continuity of therapy. For example, patients using a stationary oxygen concentrator may also use a portable oxygen concentrator as a backup option when leaving the home or during power outages, based on clinical guidance.[3]
Working With Your Healthcare Provider [5,7]
Once your physician prescribes supplemental oxygen therapy, you’ll be referred to an oxygen supplier. Your oxygen supplier is not your doctor and cannot make decisions for you and your oxygen, but they can make equipment recommendations. Many oxygen suppliers have respiratory therapists or other oxygen professionals on staff who will help you select a device that complies with your prescription and supports your lifestyle. You can also contact an Inogen Oxygen Specialist or search for oxygen suppliers on the Medicare website at www.medicare.gov/medical-equipment-suppliers. Once you have your equipment, you generally cannot change the type of equipment or type of delivery system for five years without medical necessity.
When you get your oxygen equipment, be sure to have the respiratory therapist, technician or delivery person show you how to use it. You may want to ask questions like:
- “Will I be able to do my normal activities while using this equipment?”
- “What should I do if I feel short of breath while using my oxygen?”
- “Who should I call if my equipment isn’t working?”
Comparing 5L and 10L Oxygen Concentrators
There are several key features to consider when selecting an oxygen concentrator. That said, remember to always consult with a healthcare provider before choosing a device. Current guidelines require clinical assessment and lifestyle review to ultimately determine the best choice of oxygen delivery equipment.[1,2]
Maximum Flow Rate and Delivery Capacity
The defining specification separating these 5L and 10L oxygen concentrators is maximum oxygen output, measured in liters per minute (or sometimes shown as milliliters per minute). This difference directly impacts which device will effectively deliver your prescribed therapy and whether it can adequately support your needs over time.[3]
Size, Weight, and Portability Factors
5L oxygen concentrators typically weigh between 33-36 pounds on average and measure approximately 24″ H x 13″ W x 12″ D, which is similar in size to a large, checked airline suitcase. Smaller and lighter units are available today for patients prioritizing portability. The Inogen At Home® stationary oxygen concentrator, weighing in at approximately 18 pounds, is one of the lightest home oxygen concentrators available, often coming in at half the weight of other home concentrators in use today. The compact design makes it easier to move from room to room or transport out of the home as needed.
10L units tend to be heavier, weighing between 43-60 pounds, some may be larger in size than the 5L versions. Most home oxygen concentrators have casters to make it easier to move the device from room to room.
Power Usage and Energy Efficiency
Because they are designed to run continually, energy consumption may be a concern to some home oxygen concentrator users.[3] 5L models draw 275-400 watts on average, which is roughly comparable to running several light bulbs simultaneously. However, some models such as the Inogen At Home® are designed to be energy-efficient, using just 100 watts at flow setting. 10L concentrators tend to use more power, ranging from 400-1,000 watts, depending on the model.
Home oxygen concentrators are reliable, but they depend on electricity and can be affected by power outages, equipment malfunction, or routine maintenance. For this reason, major respiratory organizations recommend that patients using concentrators have a backup oxygen source available at all times to ensure uninterrupted therapy.[3]
Noise Levels and Home Comfort
Noise level may be a clinical and quality-of-life concern for patients using home oxygen concentrators — and it’s not just about comfort. It affects sleep, anxiety, adherence, communication, and overall well-being, which is why respiratory organizations consistently highlight noise as a factor in device selection.[1]
5L concentrators typically operate between 40 and 48 decibels — roughly comparable to a quiet library or a refrigerator hum. 10L units tend to run louder, generally falling between 50 and 60 decibels due to their larger capacity and higher power demands.
Portable concentrators tend to be quieter than higher-output models; however, both are quiet enough for most daily activities and rest without significant disruption.
Cost: Purchase and Rental Options
Selecting an oxygen concentrator often involves deciding whether to rent or purchase your equipment. The best choice depends on how long you’ll need oxygen therapy, your insurance coverage, and your lifestyle needs.[5] Respiratory organizations and home-care guidelines consistently note that short-term oxygen therapy is usually more cost-effective when rented, while long-term or permanent oxygen needs often make purchasing a concentrator more economical over time.[1]
5L concentrators can start at around $600 for basic models up to $2,400 for units with more advanced features and higher flow precision. 10L models are considerably more expensive, ranging upwards of $2,000 depending on specifications.*
Your care provider or equipment specialist can help you weigh which approach best fits your situation.
*Based on 2026 cost estimates.
Comparing 5-Liter and 10-Liter Oxygen Concentrators at a Glance
The table below puts the key specifications side by side so you can see at a glance how these two concentrator categories differ across the factors that matter most to daily oxygen therapy.
Feature Comparison: 5-Liter vs 10-Liter Oxygen Concentrators
|
Attribute
|
5-Liter
Oxygen Concentrator
|
10-Liter
Oxygen Concentrator
|
|
Maximum Flow Rate
|
Up to 5 LPM
|
Up to 10 LPM
|
|
Weight Range
|
18 to 36 pounds
|
43 to 60 pounds
|
|
Typical Dimensions
|
Approximately 24″ H x 13″ W x 12″ D
|
Similar to 5L models
|
|
Power Consumption
|
100 to >400 watts
|
400 to >1,000 watts
|
|
Portability
|
Lighter weight makes it easier to move room-to room
Most models have casters
Some models available as portable units
|
Heavier than 5L models;
Available exclusively as home systems
Most models have casters
|
|
Noise Level
|
40 to 48 dBA (library-quiet conditions)
|
50 to 60 dBA
|
|
Cost Range*
|
$600+
|
$2,000+
|
|
Typical Use Cases
|
Moderate oxygen needs
|
More severe respiratory conditions requiring higher flow
|
*Based on 2026 cost estimates.
Summary
The choice between 5-liter and 10-liter oxygen concentrators depends on your prescribed flow requirements and lifestyle patterns. Depending on your oxygen therapy needs, a 5L unit may provide sufficient capacity with better portability and energy consumption, while a 10L model delivers higher flow for advanced respiratory conditions.[1-3] Noise levels, power consumption and cost differ significantly between models.
Your healthcare provider will consider your oxygen prescription, activity level, and home setup, before prescribing an oxygen delivery device. It is important to work with your clinician or care provider to determine which concentrator capacity most reliably supports your therapy goals.
If you are unsure where to start, do not hesitate to contact an Inogen Oxygen Specialist, who will be happy to help walk you through your options.
Frequently Asked Questions
How do I decide whether a 5-liter or 10-liter oxygen concentrator is right for me?
The decision depends on your prescribed oxygen flow requirements and medical condition. A 5-liter concentrator delivers up to 5 LPM may work well for patients with mild to moderate hypoxemia due to their respiratory condition. A 10-liter model provides up to 10 LPM for those with more severe conditions requiring higher oxygen flow.[1-3] Your healthcare provider will assess your specific needs, including your lifestyle, and recommend the appropriate oxygen flow rate and delivery device.[5]
What are the main differences in portability between 5-liter and 10-liter models?
5-liter home oxygen concentrators are more portable, with some models weighing under 20 pounds and featuring compact designs that make them easier to move between rooms or transport. They also tend to consume less power, making them energy efficient. In contrast, 10-liter concentrators are designed for patients with higher supplemental oxygen requirements. They are available exclusively as stationary home systems, weighing between 42-60 pounds — typically heavier than 5-liter models.[3]
Do 10-liter oxygen concentrators consume significantly more electricity than 5-liter models?
10-liter concentrators require more power to operate. 5-liter home oxygen concentrator models typically consume between 275-400 watts, about the same as a desktop computer. 10-liter concentrators draw 400-1,000 watts or more, similar to a full size refrigerator or microwave on high power.[8]
Can I use a portable oxygen concentrator if I need higher flow rates?
Portable oxygen concentrators (POCs) are generally limited to lower flow settings and pulse dose delivery. If you require continuous high-flow oxygen therapy up to 10 LPM, a stationary home concentrator is more likely to be prescribed. Some patients benefit from having both systems — a stationary unit for home and overnight use, and a portable concentrator for daytime activities. This approach should be discussed with your healthcare provider based on your specific oxygen requirements.[1,3]
How much more does a 10-liter oxygen concentrator cost compared to a 5-liter model?*
5-liter oxygen concentrators typically range from $600 to $2,400 depending on features and specifications. 10-liter concentrators are considerably more expensive, ranging from $2,000 to $4,000 or more.
*Based on 2026 cost estimates.
References
- Jacobs SS, Krishnan JA, Lederer DJ, et al. Home oxygen therapy for adults with chronic lung disease: An official ATS clinical practice guideline. Am J Respir Crit Care Med. 2020;202(10):e121–e141. doi: 10.1164/rccm.202009-3608ST
- Hardinge M, et al. Guidelines for Home Oxygen Use in Adults Thorax 2015;70:i1–i43. doi:10.1136/thoraxjnl-2015-206865 CHEST / BTS.
- Hardavella et al, Oxygen devices and delivery systems. Breathe (Sheff). 2019 Sep;15(3):e108-e116. doi: 10.1183/20734735.0204-2019. PMID: 31777573; PMCID: PMC6876135.
- MyClevelandClinic.org Oxygen Concentrators. 08/04/2023. Available from: https://my.clevelandclinic.org/health/treatments/25183-oxygen-concentrators
- COPD Foundation. COPD educational materials and downloads. Updated 2024. Available from: https://www.copdfoundation.org/Learn-More/Educational-Materials-Resources/Downloads.aspx#BasicsOxygenTherapy
- American Lung Association. Oxygen Therapy-Using Oxygen Safely. January 28, 2026. Available from: https://www.lung.org/lung-health-diseases/lung-procedures-and-tests/oxygen-therapy/using-oxygen-safely
- American Lung Association. Oxygen Therapy – Getting Started with Oxygen. January 28, 2026. Available from: https://www.lung.org/lung-health-diseases/lung-procedures-and-tests/oxygen-therapy/getting started-with-oxygen
- U.S. Department of Energy. Appliance Energy Use Reference. Residential Energy Consumption Survey (RECS). Available from: https://www.eia.gov/consumption/residential/data/2001/index.php?view=consumption
This article was authored by Inogen, Inc. and includes discussion of products manufactured by Inogen. The information provided is for general educational purposes only and is not intended to substitute for professional medical advice.